Author : Bryan Cullen
Publisher : Oxford University Press
Page : 220 pages
File Size : 25,18 MB
Release : 1993
Category : Gene Expression Regulation.
ISBN : 9780199633821
The first book to specifically cover the molecular biology of retroviruses - of immense importance since the high profile of HIV. International contributors provide detailed reviews of the latest knowledge. An excellent text for both medical and non-medical researchers, it also serves as an illuminating introduction for scientists active in other areas.
Author :
Publisher :
Page : 1254 pages
File Size : 19,6 MB
Release : 1984
Category : Oncogenic viruses
ISBN :
Author : Ann Arvin
Publisher : Cambridge University Press
Page : 1325 pages
File Size : 20,89 MB
Release : 2007-08-16
Category : Medical
ISBN : 1139461648
This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.
Author : Manja Marz
Publisher : MDPI
Page : 330 pages
File Size : 16,83 MB
Release : 2020-02-21
Category : Science
ISBN : 3039218824
Virus bioinformatics is evolving and succeeding as an area of research in its own right, representing the interface of virology and computer science. Bioinformatic approaches to investigate viral infections and outbreaks have become central to virology research, and have been successfully used to detect, control, and treat infections of humans and animals. As part of the Third Annual Meeting of the European Virus Bioinformatics Center (EVBC), we have published this Special Issue on Virus Bioinformatics.
Author : Albert Kaplan
Publisher : Elsevier
Page : 186 pages
File Size : 41,44 MB
Release : 2012-12-02
Category : Medical
ISBN : 0323160530
Viral Transformation and Endogenous Viruses is a collection of papers presented at the symposium on ""Viral Transformation and Endogenous Viruses"" held at Vanderbilt University on April 1-2, 1974. Contributors discuss the viral function(s) responsible for the transformation of the cells that are infected with oncogenic viruses, emphasizing the type of changes that characterize transformed cells and the regulatory mechanisms that are altered after malignant transformations. This volume is organized into 10 chapters and begins with an overview of DNA-containing tumor viruses, particularly Simian Virus 40 (SV40) and its mutants with DNA deletions, insertions, and duplications. The integration and transcription of adenovirus DNA is considered, along with the characteristics of temperature-sensitive mutants of these viruses. The reader is then introduced to the chemistry and biology of RNA-containing tumor viruses, which are useful reagents to study neoplastic transformation both in vivo and in vitro. A major aspect of these viruses concerns the analysis of their genome at the chemical and genetic levels. The last part of the book is devoted to biochemical and genetic analyses of endogenous viruses isolated from avian cells. This book is a valuable resource for scientists and investigators in fields such as pathology, molecular virology, molecular biology, microbiology, oncology, and biochemistry.
Author : John M. Coffin
Publisher : CSHL Press
Page : 856 pages
File Size : 41,94 MB
Release : 1997
Category : Medical
ISBN : 9780879695712
For over 25 years the study of retroviruses has underpinned much of what is known about information transfer in cells and the genetic and biochemical mechanisms that underlie cell growth and cancer induction. Emergent diseases such as AIDS and adult T-cell lymphoma have widened even further the community of investigators directly concerned with retroviruses, a development that has highlighted the need for an integrated understanding of their biology and their unique association with host genomes. This remarkable volume satisfies that need. Written by a group of the field's most distinguished investigators, rigorously edited to provide a seamless narrative, and elegantly designed for clarity and readability, this book is an instant classic that demands attention from scientists and physicians studying retroviruses and the disorders in which they play a role.
Author : Karin Moelling
Publisher : World Scientific
Page : 446 pages
File Size : 23,81 MB
Release : 2020-08-26
Category : Science
ISBN : 9811224765
Coronavirus, AIDS, and Ebola: Viruses are normally defined as pathogens. Most viruses are, however, not enemies or killers. Well-known virologist and cancer researcher Karin Moelling describes surprising insights about a completely new and unexpected world of viruses. Viruses are ubiquitous, in the oceans, our environment, in animals, plants, bacteria, in our body, even in our genomes. They influence our weather, can contribute to control obesity, and can surprisingly be applied against threatening multi-resistant bacteria. The success story of the viruses started more than 3.5 billion years ago in the dawn of life when even cells did not exist. They are the superpower of life. There are more viruses on earth than stars in the sky. Viruses are everywhere. Some of them are incredibly ancient. Many viruses are hundredfold smaller than bacteria, but others are tenfold bigger and they were discovered only recently — the giant viruses, even deep within the permafrost where they were reactivated after 30,000 years.The author talks about a completely new world of viruses, which are based on the most recent, in part her own research results. Could viruses have been our oldest ancestors? Have viruses even 'invented' social behavior, do they lead to geniuses such as Mozart or Einstein — or alternatively to cancer? They can help to cure cancer. In this book, the author made a clear distinction between what is fact and what is her vision. This book is written for a general audience and not just for the experts. Its aim is to stimulate thinking, and perhaps to attract more young scientists to enter this field of research.This revised edition is brought up to date by a new chapter on the SARS-CoV-2 pandemic. Related Link(s)
Author : Erik Lycke
Publisher : Butterworth-Heinemann
Page : 384 pages
File Size : 11,46 MB
Release : 2014-06-28
Category : Medical
ISBN : 148319194X
Textbook of Medical Virology presents a critical review of general principles in the field of medical virology. It discusses the description and molecular structures of virus. It addresses the morphology and classifications of viruses. It also demonstrates the principal aspects of virus particle structure. Some of the topics covered in the book are the symmetrical arrangements of viruses; introduction to different families of animal viruses; biochemistry of virus particles; the immunological properties and biological activities of viral gene products; description of enzymatic activities of viruses; and haemagglutination, cell fusion, and haemolysis of viruses. The description and characteristics of viral antigens are covered. The identification and propagation of viruses in tissue and cell cultures are discussed. An in-depth analysis of the principles of virus replication is provided. A study of the morphogenesis of virions is also presented. A chapter is devoted to virus-induced changes of cell structures and functions. The book can provide useful information to virologists, microbiologists, students, and researchers.
Author : R Neth
Publisher :
Page : 588 pages
File Size : 18,13 MB
Release : 1981-08-01
Category :
ISBN : 9783642679858
Author : Hung Y. Fan
Publisher : Springer Science & Business Media
Page : 272 pages
File Size : 38,44 MB
Release : 2003
Category : Medical
ISBN : 9783540440963
Ovine pulmonary adenocarcinoma (OPA) is a contagious lung cancer of sheep, first reported in South Africa in 1832 as "jaagsiekte" (chasing sickness). Starting in the 1970s evidence began to accumulate that the etiologic agent of OPA is a retrovirus, culminating in the deduction of the sequence of a novel retrovirus associated with the disease, jaagsiekte sheep retrovirus (JSRV). Very recently, substantial progress has been made in JSRV research, including isolation of infectious and oncogenic molecular clones of JSRV, identification and cloning of the JSRV receptor, and demonstration that the envelope gene of JSRV functions as an oncogene. This book is a consensus volume that comprehensively reviews all aspects of JSRV research, including natural history of the disease, histopathology of OPA, molecular biology of JSRV, oncogenic transformation by JSRV, and comparison with human lung cancer.
