What Should be Computed to Understand and Model Brain Function?


Book Description

This volume is a guide to two types of transcendence of academic borders which seem necessary for understanding and modelling brain function. The first type is technical transcendence needed to make intelligent machines such as a humanoid robot, an animal-like behavior architecture, an interpreter of fiction, and an evolving learning machine. This technical erosion is conducted into areas such as biology, ethology, neuroscience and psychology, as well as robotics and soft computing. The second type of transcendence of cross-disciplinary boundaries cuts across scientific areas such as biology and cognitive science/philosophy, into comprehensive, less technical and more abstract aspects of brain function. These aspects enable us to know in what direction and how far an intelligent machine will go.




Brain Computations


Book Description

In order to understand how the brain works, it is essential to know WHAT is computed by different brain systems, and HOW those computations are performed. This is the aim of Brain Computations: What and How. Pioneering in its approach, this book will be of interest to all scientists interested in brain function and how the brain works




The Spike


Book Description

The story of a neural impulse and what it reveals about how our brains work We see the last cookie in the box and think, can I take that? We reach a hand out. In the 2.1 seconds that this impulse travels through our brain, billions of neurons communicate with one another, sending blips of voltage through our sensory and motor regions. Neuroscientists call these blips “spikes.” Spikes enable us to do everything: talk, eat, run, see, plan, and decide. In The Spike, Mark Humphries takes readers on the epic journey of a spike through a single, brief reaction. In vivid language, Humphries tells the story of what happens in our brain, what we know about spikes, and what we still have left to understand about them. Drawing on decades of research in neuroscience, Humphries explores how spikes are born, how they are transmitted, and how they lead us to action. He dives into previously unanswered mysteries: Why are most neurons silent? What causes neurons to fire spikes spontaneously, without input from other neurons or the outside world? Why do most spikes fail to reach any destination? Humphries presents a new vision of the brain, one where fundamental computations are carried out by spontaneous spikes that predict what will happen in the world, helping us to perceive, decide, and react quickly enough for our survival. Traversing neuroscience’s expansive terrain, The Spike follows a single electrical response to illuminate how our extraordinary brains work.




Brain Computations and Connectivity


Book Description

This is an open access title available under the terms of a CC BY-NC-ND 4.0 International licence. It is free to read on the Oxford Academic platform and offered as a free PDF download from OUP and selected open access locations. Brain Computations and Connectivity is about how the brain works. In order to understand this, it is essential to know what is computed by different brain systems; and how the computations are performed. The aim of this book is to elucidate what is computed in different brain systems; and to describe current biologically plausible computational approaches and models of how each of these brain systems computes. Understanding the brain in this way has enormous potential for understanding ourselves better in health and in disease. Potential applications of this understanding are to the treatment of the brain in disease; and to artificial intelligence which will benefit from knowledge of how the brain performs many of its extraordinarily impressive functions. This book is pioneering in taking this approach to brain function: to consider what is computed by many of our brain systems; and how it is computed, and updates by much new evidence including the connectivity of the human brain the earlier book: Rolls (2021) Brain Computations: What and How, Oxford University Press. Brain Computations and Connectivity will be of interest to all scientists interested in brain function and how the brain works, whether they are from neuroscience, or from medical sciences including neurology and psychiatry, or from the area of computational science including machine learning and artificial intelligence, or from areas such as theoretical physics.




From Neurons to Neighborhoods


Book Description

How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.




The Neuroscience of Psychological Therapies


Book Description

The Neuroscience of Psychological Therapies summarizes knowledge of brain function and brain behavior relationships within the context of psychotherapy implementation. It describes how specific locations in the brain carry out specific activities, how the different activities are combined to yield normal and pathological behavior, and how knowledge of brain activities can guide psychological assessment and intervention. Specific topics include the influence of neural networks on discovery and change, the therapist's neuroscience, communicating with patients using the brain as reference, and using neuroscience concepts to compare and integrate traditional schools of psychotherapy. Applying a neuroscience framework to conceptualization and treatment of depression is offered as an example, and specific issues associated with trauma and false memories are discussed. The book is aimed at anyone working within a psychotherapy framework and who wishes to discover more about brain function and brain/behavior relationships.




Proceedings of the 1993 Connectionist Models Summer School


Book Description

The result of the 1993 Connectionist Models Summer School, the papers in this volume exemplify the tremendous breadth and depth of research underway in the field of neural networks. Although the slant of the summer school has always leaned toward cognitive science and artificial intelligence, the diverse scientific backgrounds and research interests of accepted students and invited faculty reflect the broad spectrum of areas contributing to neural networks, including artificial intelligence, cognitive science, computer science, engineering, mathematics, neuroscience, and physics. Providing an accurate picture of the state of the art in this fast-moving field, the proceedings of this intense two-week program of lectures, workshops, and informal discussions contains timely and high-quality work by the best and the brightest in the neural networks field.




Translational Research in Traumatic Brain Injury


Book Description

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme




Tinnitus - An Interdisciplinary Approach Towards Individualized Treatment: Towards Understanding the Complexity of Tinnitus


Book Description

Tinnitus - An Interdisciplinary Approach Towards Individualized Treatment: Towards Understanding the Complexity of Tinnitus, Volume 262, the latest release in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on current topics such as Cochlear implantation for patients with tinnitus – a systematic review, Event Related Potentials to Assess the Tinnitus complaint during drug treatment, The difference in post-stimulus suppression between residual inhibition and forward masking, Sleep, sleep apnea and tinnitus, A Bayesian brain in imbalance: medial, lateral and descending pathways in tinnitus and pain, Tinnitus features according to caffeine consumption, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Progress in Brain Research series - Includes the latest information on Tinnitus and its complexity




From Molecules to Minds


Book Description

Neuroscience has made phenomenal advances over the past 50 years and the pace of discovery continues to accelerate. On June 25, 2008, the Institute of Medicine (IOM) Forum on Neuroscience and Nervous System Disorders hosted more than 70 of the leading neuroscientists in the world, for a workshop titled "From Molecules to Minds: Challenges for the 21st Century." The objective of the workshop was to explore a set of common goals or "Grand Challenges" posed by participants that could inspire and rally both the scientific community and the public to consider the possibilities for neuroscience in the 21st century. The progress of the past in combination with new tools and techniques, such as neuroimaging and molecular biology, has positioned neuroscience on the cusp of even greater transformational progress in our understanding of the brain and how its inner workings result in mental activity. This workshop summary highlights the important issues and challenges facing the field of neuroscience as presented to those in attendance at the workshop, as well as the subsequent discussion that resulted. As a result, three overarching Grand Challenges emerged: How does the brain work and produce mental activity? How does physical activity in the brain give rise to thought, emotion, and behavior? How does the interplay of biology and experience shape our brains and make us who we are today? How do we keep our brains healthy? How do we protect, restore, or enhance the functioning of our brains as we age?