Author : World Health Organization
Publisher : World Health Organization
Page : 17 pages
File Size : 12,51 MB
Release : 2023-02-22
Category : Medical
ISBN : 9240069178
Author : Paul Bernard Foley
Publisher : Springer
Page : 1100 pages
File Size : 14,47 MB
Release : 2018-02-07
Category : Medical
ISBN : 1493903845
Encephalitis lethargica (‘sleeping sickness’) was a mysterious disorder that swept the world in the decade following the First World War, before disappearing without its cause having been identified. Around 85% of its victims, predominantly children, adolescents and younger adults, survived the acute disorder, but most developed severe neurological syndromes, particularly severe post-encephalitic parkinsonism and other severe motor abnormalities, that incapacitated them for the remainder of their lives. Despite its brief history, encephalitis lethargica played a major role in a variety medical discussions between the two World Wars, as this epitome of neuropsychiatric disease – attacking both motor and mental functions – appeared just as the separation of neurology and psychiatry had reached a critical point. Encephalitis lethargica sufferers presented an unprecedented combination of neurologic and psychiatric symptoms – including previously puzzling phenomena primarily associated with schizophrenia and hysteria, as well as behavioral changes and attention deficit disorders in children – that not only underscored the unity of mind and movement in the CNS, but also illuminated the critical role played by subcortical structures in consciousness and other higher mental functions that had formerly been associated with the soul and more recently presumed to be localized to the human cerebral cortex. Encephalitis lethargica exerted a greater influence on clinical and theoretic neuroscientific thought between the two World Wars than any other single disorder and had an enduring impact upon neurology and psychiatry. This book will be of interest to an educated audience active or interested in clinical (neurology, psychiatry, psychology) or laboratory neuroscience, particularly those interested in neuropsychiatry, as well as to those interested in the history of the biomedical sciences.
Author : Walter George Bradley
Publisher :
Page : 1672 pages
File Size : 44,34 MB
Release : 2004
Category : Medical
ISBN : 9780750674690
New edition, completely rewritten, with new chapters on endovascular surgery and mitochrondrial and ion channel disorders.
Author : Hideo Yamanouchi
Publisher : Elsevier Health Sciences
Page : 259 pages
File Size : 17,50 MB
Release : 2017-10-21
Category : Medical
ISBN : 0323530907
Stay current with recent progress in the field of acute encephalopathy and encephalitis in infants with this practical resource by Drs. Hideo Yamanouchi, Solomon L. Moshé, and Akihisa Okumura. This practical resource covers key information relevant to physicians, surgeons, and nurses who often must take prompt action in the everyday clinical care of patients with these disorders. - Features a wealth of information for all health care professionals who encounter these complex conditions. - Covers diagnostic strategy, subtypes of acute encephalopathy, and management of acute encephalopathy and encephalitis. - Consolidates today's available information and guidance on acute encephalopathy and encephalitis in infancy, in addition to related disorders, into one convenient resource.
Author : Susannah Cahalan
Publisher : Penguin UK
Page : 288 pages
File Size : 19,34 MB
Release : 2012-11-13
Category : Biography & Autobiography
ISBN : 0141975350
'My first serious blackout marked the line between sanity and insanity. Though I would have moments of lucidity over the coming days and weeks, I would never again be the same person ...' Susannah Cahalan was a happy, clever, healthy twenty-four-year old. Then one day she woke up in hospital, with no memory of what had happened or how she had got there. Within weeks, she would be transformed into someone unrecognizable, descending into a state of acute psychosis, undergoing rages and convulsions, hallucinating that her father had murdered his wife; that she could control time with her mind. Everything she had taken for granted about her life, and who she was, was wiped out. Brain on Fire is Susannah's story of her terrifying descent into madness and the desperate hunt for a diagnosis, as, after dozens of tests and scans, baffled doctors concluded she should be confined in a psychiatric ward. It is also the story of how one brilliant man, Syria-born Dr Najar, finally proved - using a simple pen and paper - that Susannah's psychotic behaviour was caused by a rare autoimmune disease attacking her brain. His diagnosis of this little-known condition, thought to have been the real cause of devil-possessions through history, saved her life, and possibly the lives of many others. Cahalan takes readers inside this newly-discovered disease through the progress of her own harrowing journey, piecing it together using memories, journals, hospital videos and records. Written with passionate honesty and intelligence, Brain on Fire is a searingly personal yet universal book, which asks what happens when your identity is suddenly destroyed, and how you get it back. 'With eagle-eye precision and brutal honesty, Susannah Cahalan turns her journalistic gaze on herself as she bravely looks back on one of the most harrowing and unimaginable experiences one could ever face: the loss of mind, body and self. Brain on Fire is a mesmerizing story' -Mira Bartók, New York Times bestselling author of The Memory Palace Susannah Cahalan is a reporter on the New York Post, and the recipient of the 2010 Silurian Award of Excellence in Journalism for Feature Writing. Her writing has also appeared in the New York Times, and is frequently picked up by the Daily Mail, Gawker, Gothamist, AOL and Yahoo among other news aggregrator sites.
Author : Rodrigo Hasbun
Publisher : Springer
Page : 242 pages
File Size : 48,82 MB
Release : 2018-07-19
Category : Medical
ISBN : 3319926780
Meningitis and Encephalitis are associated with high rates of mortality and neurological sequelae. The differential diagnosis includes a wide spectrum of infectious and non-infectious etiologies, some requiring urgent therapy for survival. The current management challenges in patients with meningitis and encephalitis include a low sensitivity of meningeal signs, overutilization of unnecessary screening cranial imaging, delays in diagnosis of urgent treatable causes, a large proportion of unknown etiologies, low sensitivity of current microbiological techniques especially in the setting of previous antibiotic therapy, underutilization of available molecular diagnostic tests, and empiric antibiotic therapy and hospitalization for viral meningitis cases. Even though there are published guidelines, compliance with them is not optimal and physicians do not follow standardized algorithms in their empirical approach. As meningitis and encephalitis is associated with high rates of adverse clinical outcomes, prevention, when feasible is of upmost importance. Adherence to protocols to prevent health-care associated meningitis and ventriculitis are effective but compliance with them is not uniformly performed. This book seeks to improve outcomes for meningitis and encephalitis cases handled by physicians who may or may not be thoroughly trained for these challenges. The text introduces the current guidelines but also discusses the gaps that leave clinicians struggling to implement the most appropriate approaches for these particular neurological infections. Each chapter delivers the tools necessary to identify and adhere to the most appropriate diagnostic technique, management protocols, and prevention approach for each situation. All chapters conclude with discourse on future directions in research and quality improvement. Written by experts in infectious diseases, the book covers topics that are the most devastating, including healthcare-acquired infections, autoimmune encephalitis, and infections as they present in HIV patients. Meningitis and Encephalitis is a well-rounded resource for all medical professionals encountering these neurological syndromes, including infectious disease specialists, neurologists, primary care physicians, and immunologists.
Author : Joel Vilensky, PhD
Publisher : Oxford University Press
Page : 337 pages
File Size : 27,78 MB
Release : 2010-12-15
Category : Medical
ISBN : 0199702985
Encephalitis Lethargica: During and After the Epidemic is akin to a detective novel about a major medical mystery that remains unsolved. During the 1920s and 1930s a strange, very polymorphic condition affected much of the world although not at the same time everywhere and certainly not with the same symptoms. This condition, encephalitis lethargica, could cause death in a short period, or a Rip Van Winkle type of sleep that might last days, weeks or months, but could also, surprisingly, cause insomnia. Its symptoms were thought to encompass almost anything imaginable, which made its diagnosis exceedingly difficult, to the point where its existence as a distinct neurologic entity could be questioned. Furthermore, even in those patients who appeared to recover from the disease, there was a large risk that they would subsequently develop a more chronic and devastating sequel believed to follow the disease in up to 80% of its victims, postencephalitic parkinsonism. This condition became much better known than its antecedent because of the Oliver Sacks' book, Awakenings, and the subsequent 1990 movie of the same name. Encephalitis Lethargica: During and After the Epidemic thoroughly describes the disease during the epidemic period and also details all the cases that have been reported since that time. Using language that the non-neurologist can easily understand, the book identifies the core features of this disease and tries to identify its cause. Encephalitis Lethargica: During and After the Epidemic also presents a thorough analysis of postencephalitic parkinsonism and its relationship to encephalitic lethargica. Whether this book solves the mystery of encephalitis lethargica remains to be determined, but regardless, as a result of this book, the number of clues available have been greatly increased. Accordingly, should encephalitis lethargica reappear, contemporary physicians will be prepared to diagnose and treat it because of the information provided in the book.
Author : John Mackenzie
Publisher : Springer Science & Business Media
Page : 423 pages
File Size : 24,72 MB
Release : 2012-12-06
Category : Medical
ISBN : 3642594034
Japanese encephalitis and West Nile viruses are members of the Japanese encephalitis serological group of the genus Flavivirus and therefore closely related genetically and antigenically. They share a number of properties, including the use of birds as their major wildlife maintenance host and Culicine mosquitoes for transmission, and they are both associated with severe human disease, as well as fatal infections in horses. The emergence of these two viruses, and their well-established propensity to colonise new areas, make it timely to re-examine their ecology, biology, molecular structure, replication and epidemiology, and these therefore provide the focus of this volume.
Author : Juerg Hodler
Publisher : Springer Nature
Page : 252 pages
File Size : 24,24 MB
Release : 2020-02-14
Category : Medical
ISBN : 303038490X
This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.
Author : Oliver Sacks
Publisher : Vintage
Page : 506 pages
File Size : 46,74 MB
Release : 2013-05-29
Category : Psychology
ISBN : 0307834093
The classic account of survivors of the sleeping-sickness during the great epidemic just after World War I—and their return to the world after decades of “sleep.” • “One of the most beautifully composed and moving works of our time" (The Washington Post) from the distinguished neurologist and the national bestselling author of The Man Who Mistook His Wife for a Hat. Awakenings—which inspired the major motion picture starring Robert DeNiro and Robin Williams—is the remarkable story of a group of patients who contracted sleeping-sickness during the great epidemic just after World War I. Frozen for decades in a trance-like state, these men and women were given up as hopeless until 1969, when Dr. Oliver Sacks gave them the then-new drug L-DOPA, which had an astonishing, explosive, "awakening" effect. Dr. Sacks recounts the moving case histories of his patients, their lives, and the extraordinary transformations which went with their reintroduction to a changed world.
