Your Baby's Microbiome


Book Description

"Originally published in the United Kingdom by Pinter & Martin Ltd in 2016 as The microbiome effect."




The Microbiome Effect


Book Description

At least two amazing events happen during childbirth. There's the obvious main event, which is the emergence of a new human into the world. But then there's the non-human event that is taking place simultaneously, a crucial event that is not visible to the naked eye, an event that could determine the lifelong health of the baby. This is the seeding of the baby's microbiome, the community of good bacteria that we carry with us throughout our lives. The seeding of the microbiome, along with other processes including breastfeeding, kickstarts the baby's immune system and helps to protect the infant from disease for its entire lifetime. However, with interventions like use of synthetic oxytocin, antibiotics, C-section and formula feeding, this microbial transfer from the mother to baby is interfered with or bypassed completely. Emerging research shows that bacteria are absolutely vital for human health, and imbalances in the human microbiome significantly contribute to chronic non-transmissible diseases. Drawing on the extensive research they carried out for their documentary film Microbirth, authors Toni Harman and Alex Wakeford reveal a fascinating new view of birth, and how microscopic happenings can have lifelong consequences, both for ourselves, our children and our species as a whole."




Dirt Is Good


Book Description

From two of the world’s top scientists and one of the world’s top science writers (all parents), Dirt Is Good is a q&a-based guide to everything you need to know about kids & germs. “Is it OK for my child to eat dirt?” That’s just one of the many questions authors Jack Gilbert and Rob Knight are bombarded with every week from parents all over the world. They've heard everything from “My two-year-old gets constant ear infections. Should I give her antibiotics? Or probiotics?” to “I heard that my son’s asthma was caused by a lack of microbial exposure. Is this true, and if so what can I do about it now?” Google these questions, and you’ll be overwhelmed with answers. The internet is rife with speculation and misinformation about the risks and benefits of what most parents think of as simply germs, but which scientists now call the microbiome: the combined activity of all the tiny organisms inside our bodies and the surrounding environment that have an enormous impact on our health and well-being. Who better to turn to for answers than Drs. Gilbert and Knight, two of the top scientists leading the investigation into the microbiome—an investigation that is producing fascinating discoveries and bringing answers to parents who want to do the best for their young children. Dirt Is Good is a comprehensive, authoritative, accessible guide you've been searching for.




I Contain Multitudes


Book Description

New York Times Bestseller New York Times Notable Book of 2016 • NPR Great Read of 2016 • Named a Best Book of 2016 by The Economist, Smithsonian, NPR's Science Friday, MPR, Minnesota Star Tribune, Kirkus Reviews, Publishers Weekly, The Guardian, Times (London) From Pulitzer Prize winner Ed Yong, a groundbreaking, wondrously informative, and vastly entertaining examination of the most significant revolution in biology since Darwin—a “microbe’s-eye view” of the world that reveals a marvelous, radically reconceived picture of life on earth. Every animal, whether human, squid, or wasp, is home to millions of bacteria and other microbes. Pulitzer Prize-winning author Ed Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light—less as individuals and more as the interconnected, interdependent multitudes we assuredly are. The microbes in our bodies are part of our immune systems and protect us from disease. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squid with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people. Many people think of microbes as germs to be eradicated, but those that live with us—the microbiome—build our bodies, protect our health, shape our identities, and grant us incredible abilities. In this astonishing book, Ed Yong takes us on a grand tour through our microbial partners, and introduces us to the scientists on the front lines of discovery. It will change both our view of nature and our sense of where we belong in it.




Missing Microbes


Book Description

“In Missing Microbes, Martin Blaser sounds [an] alarm. He patiently and thoroughly builds a compelling case that the threat of antibiotic overuse goes far beyond resistant infections.”—Nature Renowned microbiologist Dr. Martin J. Blaser invites us into the wilds of the human microbiome, where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the equilibrium and health of our bodies. Now this invisible Eden is under assault from our overreliance on medical advances including antibiotics and caesarian sections, threatening the extinction of our irreplaceable microbes and leading to severe health consequences. Taking us into the lab to recount his groundbreaking studies, Blaser not only provides elegant support for his theory, he guides us to what we can do to avoid even more catastrophic health problems in the future. “Missing Microbes is science writing at its very best—crisply argued and beautifully written, with stunning insights about the human microbiome and workable solutions to an urgent global crisis.”—David M. Oshinsky, author of the Pulitzer Prize-winning Polio: An American Story




The Hologenome Concept: Human, Animal and Plant Microbiota


Book Description

Groundbreaking research over the last 10 years has given rise to the hologenome concept of evolution. This concept posits that the holobiont (host plus all of its associated microorganisms) and its hologenome (sum of the genetic information of the host and its symbiotic microorganisms), acting in concert, function as a unique biological entity and therefore as a level of selection in evolution. All animals and plants harbor abundant and diverse microbiota, including viruses. Often the amount of symbiotic microorganisms and their combined genetic information far exceed that of their host. The microbiota with its microbiome, together with the host genome, can be transmitted from one generation to the next and thus propagate the unique properties of the holobiont. The microbial symbionts and the host interact in a cooperative way that affects the health of the holobiont within its environment. Beneficial microbiota protects against pathogens, provides essential nutrients, catabolizes complex polysaccharides, renders harmful chemicals inert, and contributes to the performance of the immune system. In humans and animals, the microbiota also plays a role in behavior. The sum of these cooperative interactions characterizes the holobiont as a unique biological entity. Genetic variation in the hologenome can be brought about by changes in either the host genome or the microbial population genomes (microbiome). Evolution by cooperation can occur by amplifying existing microbes, gaining novel microbiota and by acquiring microbial and viral genes. Under environmental stress, the microbiome can change more rapidly and in response to more processes than the host organism alone and thus influences the evolution of the holobiont. Prebiotics, probiotics, synbiotics and phage therapy are discussed as applied aspects of the hologenome concept.




Skin Microbiome Handbook


Book Description

The book provides a comprehensive detailed summary of current status on skin microbiome research in health and disease as well as key regulatory and legal aspects. In the past decade, interest and technology have greatly advanced to unravel the nature and effect of skin microbiome on our health. Diseases such as atopic dermatitis and acne are at the forefront of this research, but also other conditions such as skin cancer are under investigation. In addition, mapping of the skin microbiome has gone from basic to more detailed with attempts to correlate it to various ages, ethnicities and genders. In parallel to mapping it, a great deal of research is dedicated to understanding its functionality and communication (and hence effect) on human cells. The Skin Microbiome Handbook is a summary of current status of knowledge, research tools and approaches in skin microbiome, in health and disease. It contains the following categories: healthy skin microbiome and oral-skin interaction; skin microbiome observational research; skin microbiome in disequilibrium and disease; skin's innate immunity; testing and study design; regulatory and legal aspects for skin microbiome related products. The 18 chapters of the book are written by carefully selected leaders in the academia and industry exhibiting extensive experience and understanding in the areas of interest.




The Healthy Baby Gut Guide


Book Description

Childhood allergies are booming, affecting almost one in five Australian kids. But what if there was a way to prevent allergies in the first place? What if simple lifestyle changes in the critical first 1000 days could change your baby's life? For families across Australia, eczema, asthma, hay fever and food allergies are constant anxieties, sometimes with devastating consequences. Leading gastroenterologist Dr Vincent Ho has taken a deep dive into the exploding medical field of gut health and explains that from conception to birth, and from breastfeeding to the introduction of solid foods, small steps go a long way in preventing allergies and fortifying your baby's immune system. Dr Ho cuts through the scientific jargon to provide strategies for allergy management and treatment, and shows you how to strengthen your child's gut health for the long term - all before they begin to walk. The Healthy Baby Gut Guide is packed with sensible advice, surprising scientific discoveries and even a nutritionist-approved nine-week infant meal plan to help parents navigate the introduction of common allergenic foods. Practical, easy-to-follow and utterly eye-opening, this book is essential reading for every parent and parent-to-be.




The Human Microbiome, Diet, and Health


Book Description

The Food Forum convened a public workshop on February 22-23, 2012, to explore current and emerging knowledge of the human microbiome, its role in human health, its interaction with the diet, and the translation of new research findings into tools and products that improve the nutritional quality of the food supply. The Human Microbiome, Diet, and Health: Workshop Summary summarizes the presentations and discussions that took place during the workshop. Over the two day workshop, several themes covered included: The microbiome is integral to human physiology, health, and disease. The microbiome is arguably the most intimate connection that humans have with their external environment, mostly through diet. Given the emerging nature of research on the microbiome, some important methodology issues might still have to be resolved with respect to undersampling and a lack of causal and mechanistic studies. Dietary interventions intended to have an impact on host biology via their impact on the microbiome are being developed, and the market for these products is seeing tremendous success. However, the current regulatory framework poses challenges to industry interest and investment.




The Baby and the Biome


Book Description

A revolutionary parenting book that draws on cutting-edge research to reveal that the key to raising happy and healthy babies lies in carefully protecting and caring for their microbiomes. A baby’s immune system develops rapidly in the first 1,000 days of life, with the first six months and year being most important. In The Baby and the Biome, Meenal Lele, medical researcher and founder of Lil Mixins, the #1 pediatrician-recommended allergy-prevention product , explains how diet, environmental toxins, antibiotics, and even common parenting practices can damage the delicate balance of our children’s microbiomes, thereby increasing the risk for a host of immune diseases, including eczema, asthma, food allergies, IBS, and more. Lele discovered firsthand how critical our microbiomes are to our overall health when she sought to understand the root causes for her son’s food allergies. Drawing on her medical background and through extensive research and interviews with scientists and doctors, Lele discovered the simple, practical steps that all parents and pregnant moms can take to help foster a healthy and protective microbiome in their baby. The Baby and the Biome will empower parents to protect and safeguard their children’s health for years to come.