Host-Parasite Relationships and the Yersinia Model


Book Description

During the past few decades we have witnessed an era of remarkable growth in the field of molecular biology. In 1950 very little was known of the chemical constitution of biological systems, the manner in which information was transmitted from one organism to another, or the extent to which the chemical basis of life is unified. The picture today is dramatically different. We have an almost bewildering variety of information detailing many different aspects oflife at the molecular level. These great advances have brought with them some breath-taking insights into the molecular mechanisms used by nature for replicating, distributing and modifying biological information. We have learned a great deal about the chemical and physical nature of the macro molecular nucleic acids and proteins, and the manner in which carbohydrates, lipids and smaller molecules work together to provide the molecular setting of living systems. It might be said that these few decades have replaced a near vacuum of informa tion with a very large surplus. It is in the context of this flood of information that this series of monographs on molecular biology has been organized. The idea is to bring together in one place, between the covers of one book, a concise assessment of the state of the subject in a well-defined field. This will enable the reader to get a sense of historical perspective what is known about the field today - and a description of the frontiers of research where our knowledge is increasing steadily.




Defending Life


Book Description

Defending Life discusses the relationship between hosts and parasites. It contains detailed descriptions of the immune system and the microbial world as well as methodological and conceptual clarifications. Its emphasis on analytical abstractions, coherent patterns and generative mechanisms makes possible the distinction between genuine causality and coincidental associations and increases the understanding of why we observe what we observe.




Host-Parasite Interactions


Book Description

This volume summarizes current research into the physiology and molecular biology of host-parasite interactions. Brought together by leading international experts in the field, the first section outlines fundamental processes, followed by specific examples in the concluding section. Covering a wide range of organisms, Host-Parasite Interactions is essential reading for researchers in the field.




The Influence of Antibiotics on the Host-Parasite Relationship II


Book Description

The Second International Symposium on "The Influence of Antibiotics on the Host Parasite Relationship" was held in Munich, F. R. G. , from March 28 to 30,1985. The topics of the meeting dealt with the aspects of changes in bacterial metabolism and structure which occur under the influence of antibiotics, and with the effects of such changes on the antibacterial host resistance. The influence on pathogenicity factors, changes in the outer membrane of bacteria, as well as the influence on the individual components of the defence system were analysed in detail. In addition, these studies showed that antibiotics proved to be an excellent tool for the examination of bacterial physiology, so that, 50 years after the introduction of antibiotics, additional important knowledge can be gained about the effect of these substances on bacteria. Considering the observations reported, it appears justifiable to postulate that new antibiotics should be routinely tested with respect to their possible effects on antiinfectious resistance. Of course, a consensus will have to be found on which to base methods and criteria employ€d. The symposium documented an increasing interest of microbiologists and clini cians for this field of research. It would not have been possible to organize it without the substantial support of the Paul Ehrlich Society as well as of Squibb-Von Heyden Pharma, Inc. Particular help concerning the organization has been given by Werner Kremer of Squibb-Von Heyden Pharma.




Biochemical, Immunological and Epidemiological Analysis of Parasitic Diseases


Book Description

This book comprehensively reviews various vector-borne diseases and their control methods. It discusses morphology, life history, and pathogenicity of protozoan and helminth parasites. Further, it analyzes host-parasite interactions and their adaptation within the host system for understanding parasitic infections. The book discusses the complex life cycle, biochemical adaptations, and molecular biology of the parasites. It investigates the immunological response to different infectious agents and explores new targets for combined therapeutic approaches. It also summarizes the evolution of parasitism and the ecology of parasites of the different phylum. Lastly, it provides information on vector biology emphasizing the role of basic vector research in developing future disease control methods and improving upon the existing approaches.